SCLEROSING LYMPHANGITIS OF THE PENIS / LINFANGITIS ESCLEROSANTE DEL PENE.

 Sclerosing Lymphangitis of the penis.

Linfangitis esclerosante del pene.

EDITORIAL ENGLISH

===================
Hello friends, DERMAGIC again with you, the today topic SCLEROSING LYMPHANGITIS OF THE PENIS. This pathology is really NOT VERY WELL-KNOWN, and for that reason I present it today. 

Some authors have associated it to POST herpes genitalis, Chlamydia, and syphilis, Others authors intend to always discard mainly SYPHILIS in this condition. ALL these are sexually transmitted diseases (STD), then it is necessary to think that a VENEREAL AND NON-VENEREAL variants exists.
 

The non-venereal variant probably ASSOCIATED TO LOCAL TRAUMATISM (masturbation and sexual relationships). OTHER authors relate it to antigens related with the factor VIII of the clotting and they propose the I TERM of MONDOR'S phlebitis OF THE PENIS. 

The VENEREAL variant is obviously related to sexually transmitted diseases(STD)  as I already mention
 

The treatment an entire challenge for any dermatologist, in general the disease disappears in several weeks with a good treatment in the VENEREAL variant, and it is recommended not sexual relationships and masturbation to avoid the local trauma, maybe the main factor that causes the NON-VENEREAL variant.

In these 41 references the facts, in the photo a classic SCLEROSING LYMPHANGITIS OF THE PENIS

Greetings to all.

Dr. Jose Lapenta.

 

EDITORIAL ESPAÑOL 
===================
Hola amigos DERMAGIC de nuevo con ustedes, el tema de hoy LA LINFANGITIS ESCLEROSANTE DEL PENE. Esta patología realmente es POCO CONOCIDA, por muchos y por ello la presento hoy.

Se ha asociado a cuadros POST herpes genital, Clamydia y sífilis.  Otros .autores proponen descartar principalmente (SIFILIS) en esta condición. TODAS estas son enfermedades de transmisión sexual (ETS), entonces hay que pensar que existe una variante VENEREA Y OTRA NO VENEREA. 

 

La variante NO VENEREA probablemente ASOCIADA A TRAUMATISMO LOCAL (masturbación y relaciones sexuales). OTROS autores la relacionan a antígenos relacionados con el factor VIII de la coagulación y proponen el termino de FLEBITIS DE MONDOR DEL PENE. 

La variante VENEREA obviamente esta asociada a enfermedades de transmisión sexual (ETS), como les mencione.

El tratamiento es todo un reto para cualquier dermatólogo, por lo general la enfermedad desaparece en varias semanas con un buen tratamiento, variante VENEREA y se recomienda evitar relaciones sexuales y masturbación para evitar el trauma local, uno o quizá el principal factor que ocasiona la variante NO VENEREA.

En las 41referencias los hechos, y en la foto una clásica LINFANGITIS ESCLEROSANTE DEL PENE.

 Saludos a todos... 

 Dr. José Lapenta R. 

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 REFERENCIAS BIBLIOGRAFICAS / BIBLIOGRAPHICAL REFERENCES 
 ============================================================
 0.) SCLEROSING LYMPHANGITIS OF THE PENIS. THE HISTORY
 1.) Non-venereal sclerosing lymphangitis of the penis following herpes progenitalis.
 2.) Nonvenereal sclerosing lymphangitis of the penis.
3.) [Sclerosing lymphangitis of the penis, the upper lip and the labium minus]
4.) Nonvenereal sclerosing lymphangitis of the penis.
5.) Non-venereal sclerosing lymphangitis of the penis.
6.) Non-venereal sclerosing lymphangitis of the penis. A clinicopathologic treatise.
7.) Mondor's phlebitis of the penis. A condition miscalled 'non-venereal sclerosing lymphangitis'.
8.) Circular indurated lymphangitis of the penis.
9.) [Indications for corticotherapy in phlebology]
10.) [A case for diagnosis: sclerosing lymphangitis of the penis].
11.) [Non-venereal sclerosing lymphangitis of the penis].
12.) [Non-venereal sclerosing lymphangitis of the penis].
13.) Nonvenereal sclerosing lymphangitis of the penis.
14.) [A case of non-venereal sclerosing lymphangitis of the penis].
15.) [A case of Mondor's disease of the penis].
16.) Non-venereal sclerosing lymphangitis of the penis associated with masturbation.
17.) [2 cases of sclerosing lymphangitis of the sex organs].
18.) Mondor's phlebitis of the penis: a study with factor VIII related antigen.
19.) [Non-venereal sclerosing lymphangitis of the penis revealed as phlebitis by positive factor
VIII-related antigen].
20.) Surgical management of persistent, symptomatic nonvenereal sclerosing lymphangitis of the penis.
21.) Sclerosing lymphangitis of the penis: a lymphangiofibrosis thrombotica occlusiva.
22.) Sclerosing lymphangitis of the penis: a possible chlamydia aetiology.
23.) [Development of non-venereal sclerosing lymphangitis of the penis following herpetic balanitis].
24.) [Case of sclerosing lymphangitis of the sex organs].
25.) [Nonveneral sclerosing lymphangitis of the penis].
26.) Benign transient lymphangiectasis (sclerosing lymphangitis) of the penis.
27.) [Sclerosing lymphagitis of the penis].
28.) Lymphocoele and localized lymphoedema of the penis.
29.) Nonvenereal sclerosing lymphangitis of the penis.
30.) Sclerosing non-venereal lymphangitis of the penis].
31.) Sclerosing lymphangitis of the penis.
32.) Nonvenereal sclerosing lymphangitis of the penis.
33.) Nonvenereal sclerosing lymphangitis of the penis.
34.)The so-called Hoffman's lymphangitis of the penis: is it a lymphangitis or a phlebitis?
35.) Sclerosing lymphangitis of penis - literature review and report of 2 cases.
36.) Sclerosing lymphangitis of the penis after coadministration of tadalafil and fluconazole.
37.) [Mondor's disease vs. sclerosing lymphangitis of the penis].
38.) Immunohistochemical clues to the diagnosis of Mondor's disease of the penis.
39.) [Non venereal sclerosing lymphangitis of the penis. Case report].
40.) Mondor's disease of the penis associated with primary syphilis.
41.) Mondor's disease of penis: a forgotten disease.

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0.) SCLEROSING LYMPHANGITIS OF THE PENIS. THE HISTORY
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SOURCE: MED HELP INTERNATIONAL
Forum: The Urology Forum
Question Posted By: Jonathan on Thursday, December 30, 1999


I have a condition that in many respects appears to be sclerosing lymphangitis - a vein-like fibrous area under the skin, just below or medial from the glans, on the left side of the penis, going around the circumference. The left end can move or when I touch it, but on the right end seems to be connected internally. When I am not erect, it is about 1/2 inch long and 1/16 inch wide. When I am erect or it is irritated, it is 3/4 inch long and 1/8 inch wide. When I am having sex, it can fairly easily become painful and/or swollen.

I first encountered it about 10 years ago, after a period of intense masturbation. The problem is that it has not gone away, though I have had periods of a month or more with no sexual activity or masturbation. In the last year, it has gotten worse in that it is longer, more prominent during sexual activity, and more often painful. Often I feel a soreness or itchiness (under the skin surface) after sexual activity. Using a condom tends to increase the symptoms.

Recently, I have seen a couple of dermatologists about this, one of whom suggested that it may be sclerosing lymphangitis. I then went to two urologists, neither of whom was familiar with the term. All have said that there is no STD or other such problem is present.

So my question is - are there non-surgical ways of helping this heal? And if it persists, how do I find urologists who have treated this problem?

Thank you.


Answer Posted By: HFHS M.D.-BL on Thursday, December 30, 1999

Dear Jonathan,

Sclerosing lymphangitis is a translucent cordlike lesion that occurs on the shaft of glans of the penis. It is usually flesh-colored but may appear slightly red. It is most commonly associated with vigorous sexual activity, but it is also seen with infections including gonorrhea, syphilis, chlamydia, and herpes. When biopsy specimens are looked at under the microscope, thrombosed lymphatic vessels are seen. The thrombosis of these vessels is theorized to be secondary to the local trauma.


Most cases of Sclerosing Lymphangitis of the penis are not painful and remit within several weeks. Treatment has traditionally consisted of avoidance of vigorous sexual activity until the lesion disappears. I am not sure how long you initially went without sex once you were given a preliminary diagnosis, but you may have started sexual activity too soon. Unfortunately a true diagnosis of Sclerosing Lymphangitis would necessitate a biopsy and examination under a microscope, but this is rarely required. This disorder is usually self-limited (lasting only a few weeks), but in a few rare cases in which there are persistent symptomatic lesions surgery is indicated. For a rare and confusing case such as yours I would suggest that you seek a urologist at an academic hospital with a Urology residency training program.


This information is provided for general medical educational purposes only. Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition. More individualized care is available at the Henry Ford Hospital and its satellites (1 800 653-6568).

============================================================
1.) Non-venereal sclerosing lymphangitis of the penis following herpes progenitalis.
============================================================
SO - Br J Dermatol 1977 Jun;96(6):679-80
AU - Van de Staak WJ
PT - JOURNAL ARTICLE
AB - Two patients are described in which non-venereal sclerosing lymphangitis of the penis
occurred immediately after a herpes simplex infection. The possibility of a causal relationship
between these two conditions is discussed.

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2.) Nonvenereal sclerosing lymphangitis of the penis.
============================================================
SO - Arch Dermatol 1975 Jul;111(7):902-3
AU - Fiumara NJ
PT - JOURNAL ARTICLE
AB - Sclerosing lymphangitis of the penis with a purplish, cord-like structure, singular or multiple
around the coronal sulcus, appears 24 to 48 hours after sexual relations. There is edema of the glans
penis and coronal area, which is doughy and plastic. The condition is self-limited.

============================================================
3.) [Sclerosing lymphangitis of the penis, the upper lip and the labium minus]
============================================================
SO - Hautarzt 1974 May;25(5):231-7
AU - Stolz E; Kampen WJ van; Vuzevski V
PT - JOURNAL ARTICLE

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4.) Nonvenereal sclerosing lymphangitis of the penis.
============================================================
SO - Arch Dermatol 1972 May;105(5):728-9
AU - Greenberg RD; Perry TL
PT - JOURNAL ARTICLE

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5.) Non-venereal sclerosing lymphangitis of the penis.
============================================================
SO - Br J Dermatol 1970 Jun;82(6):632-3
AU - Boyd AS
PT - JOURNAL ARTICLE

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6.) Non-venereal sclerosing lymphangitis of the penis. A clinicopathologic treatise.
============================================================
SO - Acta Derm Venereol 1970;50(4):309-12
AU - Kandil E; al-Kashlan IM
PT - JOURNAL ARTICLE

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7.) Mondor's phlebitis of the penis. A condition miscalled 'non-venereal sclerosing lymphangitis'.
============================================================
SO - Clin Exp Dermatol 1977 Mar;2(1):65-7
AU - Findlay GH; Whiting DA
PT - JOURNAL ARTICLE

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8.) Circular indurated lymphangitis of the penis.
============================================================
SO - Arch Dermatol 1976 Aug;112(8):1146
AU - Baden HP; Provan J; Tanenbaum L
PT - JOURNAL ARTICLE
AB - Circular lymphangitis of the penis has been seen in three of our patients, two of whom
complained of mild discomfort. A patient with syphilis was initially misdiagnosed because of similar
clinical findings. A serologic test for syphilis should be performed in all patients with this disorder.

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9.) [Indications for corticotherapy in phlebology]
============================================================
SO - Phlebologie 1979 Oct-Dec;32(4):375-82
AU - Chatard H
MC - English Abstract
PT - JOURNAL ARTICLE
AB - Corticosteroid therapy has not revolutionised phlebology but it is very useful in certain cases.
The following indications are considered, with or without associated antibiotics : anaphylactic shock
after sclerosant injections, chronic lymphangitis of the lower limbs, sclero-inflammatory
hypodermatitis, eczemas, phlebitis, ulcers and angiomas. Various forms of corticosteroid therapy are
considered ; injectable, long-acting, local and oral.

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10.) [A case for diagnosis: sclerosing lymphangitis of the penis].
============================================================
Ann Dermatol Venereol 1994;121(4):351-2

[Article in French]

Alfandari S, Delaporte E, Piette F, Bergoend H

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11.) [Non-venereal sclerosing lymphangitis of the penis].
============================================================
Arch Esp Urol 1992 Sep;45(7):705-7

[Article in Spanish]

Murillo Mirat J, Soler Fernandez J, Torrubia Romero FJ, Caballero Gomez M, Herrera Puerto J

Servicio de Urologia del Hospital Regional Infanta Cristina, Badajoz, Espana.

Non-venereal sclerosing lymphangitis of the penis is a rare condition that affects the distal lymphatics
of this organ. It has been reported to be frequently associated with trauma to this area and, although
it has a minimum inflammatory component, its etiology is unknown. A serpinginous nodular lesion in
the sulcus coronarius penis may be observed by the patient. Because it is generally self-limiting,
treatment is initially conservative and surgical excision is performed only if symptomatic lesions
persist. The present study reports an additional case. The literature is reviewed and the possible
etiopathogenic mechanisms and therapeutic alternatives are discussed.

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12.) [Non-venereal sclerosing lymphangitis of the penis].
============================================================
Minerva Urol Nefrol 1992 Jan-Mar;44(1):47-8

[Article in Italian]

Aragong F

Publication Types:
Letter
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13.) Nonvenereal sclerosing lymphangitis of the penis.
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Cutis 1991 Jun;47(6):421-2

Gharpuray MB, Tolat SN

Department of Dermatology, B.J. Medical College, Maharashtra, India.
============================================================
14.) [A case of non-venereal sclerosing lymphangitis of the penis].
============================================================
Minerva Urol Nefrol 1991 Jan-Mar;43(1):47-8

[Article in Italian]

Bodo G, Ollino M, Bellandini R

Divisione di Urologia, USSL n. 40, Ospedale Civile, Ivrea, Torino.

The Authors describe a case of non venereal sclerosing lymphangitis of the penis. They also delineate
the differential diagnosis, the causes and the therapies of this disease.

============================================================
15.) [A case of Mondor's disease of the penis].
============================================================
Hinyokika Kiyo 1988 Jul;34(7):1245-8

[Article in Japanese]

Doi Y, Takeyama M, Matsui T, Fujioka H

Department of Urology, Osaka Central Hospital.

A case of Mondor's disease of the penis in a 40-year-old man is reported. The patient complained
of a small subcutaneous induration (0.5 x 1.0 cm) with slight tenderness in the dorsal region of the
penile shaft. On examination, the linear cord was palpated running both distally and proximally from
the induration. This lesion was removed under local anesthesia, and the induration and the cord were
found to be part of the superficial dorsal vein of the penis. The venous wall was thick and the
thrombus was packed in it. Histological findings showed the proliferation of connective tissue of the
vessel wall and partially granulating thrombus in the canal. From these findings, we confirmed the
diagnosis of Mondor's disease of the penis. The etiology of this disease, especially in comparison
with non-venereal sclerosing lymphangitis of the penis (N.S.L.P.) is discussed.

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16.) Non-venereal sclerosing lymphangitis of the penis associated with masturbation.
============================================================
Br J Urol 1987 Feb;59(2):194-5 Related Articles, Books, LinkOut

Sieunarine K

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17.) [2 cases of sclerosing lymphangitis of the sex organs].
============================================================
Vestn Dermatol Venerol 1984 Sep;(9):64-5

[Article in Russian]

Vitenchuk SZ, Mitrofanova NB, Belov AS
============================================================
18.) Mondor's phlebitis of the penis: a study with factor VIII related antigen.
============================================================
Acta Derm Venereol 1984;64(4):337-40 Related Articles, Books, LinkOut

Tanii T, Hamada T, Asai Y, Yorifuji T

Four patients with so-called non-venereal sclerosing lymphangitis of the penis are reported. It was
suggested that the affected vessels were veins by positively stained factor VIII related antigen with
the unlabeled peroxidase-antiperoxidase method. If cord-like linear subcutaneous swelling observed
in the coronary sulcus or dorsal region of the penile shaft originate from the vein, it seems correct to
call this disease as Mondor's phlebitis of the penis.

============================================================
19.) [Non-venereal sclerosing lymphangitis of the penis revealed as phlebitis by positive factor
VIII-related antigen].
============================================================
Nippon Hifuka Gakkai Zasshi 1983 Nov;93(12):1347-9

[Article in Japanese]

Tanii T, Hamada T, Asai Y, Yorifuji T

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20.) Surgical management of persistent, symptomatic nonvenereal sclerosing lymphangitis of the penis.
============================================================
J Urol 1982 May;127(5):987-8
Broaddus SB, Leadbetter GW

Nonvenereal sclerosing lymphangitis of the penis is a rare condition involving the distal lymphatics of
the penis. Its association with trauma has been shown. Although there is a minimal inflammatory
response the etiology is unknown. Clinically, the patient notices a nontender, serpiginous nodular
mass just proximal to the coronal sulcus. Most cases are self-limited and conservative management is
indicated. Surgical excision is warranted for persistently symptomatic lesions.


============================================================
21.) Sclerosing lymphangitis of the penis: a lymphangiofibrosis thrombotica occlusiva.
============================================================
Br J Dermatol 1981 Jun;104(6):687-95


Marsch WC, Stuttgen G

Three patients with so-called non-venereal sclerosing lymphangitis of the penis are presented. Light
and electron microscopy of one case revealed a lymphatic collecting vessel with a fibrin thrombus in
the process of recanalization and vessel wall fibrosis due to hyperplasia of smooth muscle cells and
fibroblasts. The term 'lymphangiofibrosis thrombotica occlusiva' is proposed. Lymph stasis is
suggested as a provoking factor for the dilatation and clinically striking firm thickening of the affected
collecting vessel. No microorganisms were recognized. Within the fibrin thrombus, sprouts of
endothelial cells showed intracellular vacuoles, probably indicating the first identifiable step in lymph
capillary lumen formation. Signs of collagen remodelling were encountered in the thickened vessel
wall.


============================================================
22.) Sclerosing lymphangitis of the penis: a possible chlamydia aetiology.
============================================================
Acta Derm Venereol 1981;61(5):455-6

Kristensen JK, Scheibel J


============================================================
23.) [Development of non-venereal sclerosing lymphangitis of the penis following herpetic balanitis].
============================================================
Cesk Dermatol 1979 Dec;54(6):361-3

[Article in Slovak]

Farkas J
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============================================================
24.) [Case of sclerosing lymphangitis of the sex organs].
============================================================
Vestn Dermatol Venerol 1978 Nov;(11):58-61


[Article in Russian]

Torsuev NA, Bukharovich MN
============================================================
============================================================
25.) [Nonveneral sclerosing lymphangitis of the penis].
============================================================
Actas Dermosifiliogr 1978 Sep-Oct;69(9-10):309-12

[Article in Spanish]

Moreno Izquierdo R, Merino Monge E, Guerra Tapia A, Barrio Fuertes A

============================================================
============================================================
26.) Benign transient lymphangiectasis (sclerosing lymphangitis) of the penis.
============================================================
Br J Vener Dis 1977 Dec;53(6):379-85

Hutchins P, Dunlop EM, Rodin P


============================================================
27.) [Sclerosing lymphagitis of the penis].
============================================================
Ned Tijdschr Geneeskd 1977 Oct 8;121(41):1597-8

[Article in Dutch]

Neering H, Starink TM

============================================================
28.) Lymphocoele and localized lymphoedema of the penis.
============================================================
Br J Vener Dis 1976 Dec;52(6):409-11


McMillan A

Six patients with lymphocoele or sclerosing lymphangitis of the penis attended the Department of
Venereology, Royal Infirmary, Edinburgh, during a 9-month period. Clinical details of these patients
are given and the aetiology of the condition is discussed.

============================================================
29.) Nonvenereal sclerosing lymphangitis of the penis.
============================================================
Arch Dermatol 1975 Jul;111(7):902-3

Fiumara NJ

Sclerosing lymphangitis of the penis with a purplish, cord-like structure, singular or multiple around
the coronal sulcus, appears 24 to 48 hours after sexual relations. There is edema of the glans penis
and coronal area, which is doughy and plastic. The condition is self-limited.


============================================================
30.) Sclerosing non-venereal lymphangitis of the penis].
============================================================
Minerva Med 1973 Dec 26;64(93):4967-70

[Article in Italian]

Matheis H

============================================================
31.) Sclerosing lymphangitis of the penis.
============================================================
Br J Vener Dis 1972 Dec;48(6):545-8 Related Articles, Books, LinkOut

Lassus A, Niemi KM, Valle SL, Kiistala U
============================================================

============================================================
32.) Nonvenereal sclerosing lymphangitis of the penis.
============================================================
Arch Dermatol 1972 May;105(5):728-9

Greenberg RD, Perry TL


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33.) Nonvenereal sclerosing lymphangitis of the penis.
========================================================
South Med J. 2009 Dec;102(12):1269-71. doi: 10.1097/SMJ.0b013e3181bf27f6.

Yap FB1.
Author information

1Department of Dermatology, Sarawak General Hospital, Sarawak, Malaysia. woodzlamp@yahoo.com

Abstract

A 30-year-old man presented to the genitourinary medicine clinic with the sudden appearance of an asymptomatic, 2 mm wide, flesh-colored, firm, and cord-like lesion encircling the coronal sulcus circumferentially following vigorous sexual intercourse with his wife. An initial diagnosis of sexually transmitted disease-associated penile swelling was entertained. He was given antibiotics for this condition. Failure of resolution and negative screening tests for sexually transmitted diseases prompted a skin biopsy and extensive literature search, with an ultimate diagnosis of nonvenereal sclerosing lymphangitis of the penis, a rare, self-limiting condition. Reassurance and abstinence of sexual intercourse for a few weeks led to complete recovery.
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34.)The so-called Hoffman's lymphangitis of the penis: is it a lymphangitis or a phlebitis?
============================================================================
. Int Urol Nephrol. 1988;20(2):139-45.

Aragona P1, Piazza R, Artibani W, Dante S.
Author information

1Institute of Urology, University of Padua, Italia.

Abstract

Hoffman's plastic lymphangitis of the penis is a benign, uncommon entity whose aetiology is still unknown. Microscopically there is a fibrous thickening of the involved lymph vessels but the primary localization of the lesion--lymphatic or venous--is still debated. Anatomo-clinical and histological findings suggest a primary involvement of the lymphatic system of the penis, probably related to a prolonged period of sexual excitement.
============================================================
35.) Sclerosing lymphangitis of penis - literature review and report of 2 cases.
============================================================
Dermatol Online J. 2014 Jul 15;20(7). pii: 13030/qt7gq9h1v9.

Babu AK1, Krishnan P, Andezuth DD.
Author information

1Sree Narayana Institute of Medical Sciences, India.

Abstract

Sclerosing lymphangitis of the penis is a condition related to vigorous sexual activity, manifesting as an asymptomatic firm cord -like swelling around the coronal sulcus of the penis. Since, it is self-limiting, only reassurance along with abstinence from sexual activity are required. In addition to reporting two new cases, we review and discuss the medical literature for this condition.
============================================================================
36.) Sclerosing lymphangitis of the penis after coadministration of tadalafil and fluconazole.
============================================================================
Clin Exp Dermatol. 2009 Oct;34(7):e225-6. doi: 10.1111/j.1365-2230.2008.03068.x.

Guarneri C, Polimeni G.
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37.) [Mondor's disease vs. sclerosing lymphangitis of the penis].
=====================================================================
Arch Esp Urol. 2008 Sep;61(7):837-40.

[Article in Spanish]
Ramos Barseló E1, Portillo Martín JA, Correas Gomez M, Gutierrez Baños JL, Aguilera Tubet C, Ballestero Diego R, Zubillaga Guerrero S, Campos Sañudo JA, Hidalgo Zabala E, García-Barón PL, Lopez Rasines G.
Author information

1Servicio de Urologiá, Hospital Universitario Marqués de Valdecilla, Facultad de Medicina, Universidad de Cantabria, Santander, España. enriqueramosbarselo@hotmail.com

Abstract
OBJECTIVE:

Two cases of Mondor's disease and one case of non-venereal sclerosing lymphangitis of the penis are reviewed. We analyze the differences between both processes based on the existing literature about these pathologies.
METHOD:

Two clinical cases of Mondor's disease and other one with non-venereal sclerosing lymphangitis are reported.
RESULTS:

Due to the spontaneous and good outcome of both pathologies, the diagnosis and follow-up are difficult in both processes.
CONCLUSIONS:

Doppler ultrasound has a great importance for the differential diagnosis between both processes. The treatment is based on steroidal anti-inflammatories as well as sexual abstinence.
==============================================================
38.) Immunohistochemical clues to the diagnosis of Mondor's disease of the penis.
=============================================================
Clin Exp Dermatol. 2009 Dec;34(8):e663-5. doi: 10.1111/j.1365-2230.2009.03381.x. Epub 2009 Jun 22.

Alvarez-Garrido H1, Sanz-Muñoz C, Pericet-Fernández L, Garrido-Ríos AA, Miranda-Romero A.
Author information

1Department of Dermatology, Hospital Clinico Universitario, Valladolid, Spain. helenaalvarezgarrido@hotmail.com

Abstract

Mondor's disease of the penis is usually a benign, self-limiting process of acute onset. To date, there have been few studies about its diagnosis and treatment. It is difficult to differentiate MD of the penis from sclerosing lymphangitis of the penis, because the symptoms, epidemiology and aetiology are similar, and because veins are histologically very similar to lymphatics. We report a case of MD in which immunochemical markers such as CD31 and D240 allowed us to specifically discriminate between the small vein and lymphatic vessels. This is important not only for the recognition of MD at any site, but for many other diseases in which veins or lymphatic vessels are affected.
===========================================================
39.) [Non venereal sclerosing lymphangitis of the penis. Case report].
===========================================================
Arch Esp Urol. 2007 Apr;60(3):298-300.

[Article in Spanish]
Mateos Blanco J1, Ramírez Zambrana A, Molina Suárez JL, Alarcón del Viejo C, Cabello Padial J, Mariño del Real J, Laguna Pérez E.
Author information

1Servicio de Urología, Hospital Infanta Cristina, Complejo Hospitalario Universitario de Badajoz, Badajoz, España. jesus_mateo@terra.es

Abstract
OBJECTIVE:

We report a clinical case with a diagnosis of nonvenereal sclerosing lymphangitis of the penis and revision of the literature existing on this pathology.
CLINICAL CASE:

We describe the case of a 28 years old man who has presented for 10 days an induration of cartilaginous consistence next to the sulcus coronarius penis and symptomatic during the erections, compatible with the diagnosis of sclerosing lymphangitis.
RESULTS:

Sexual abstinence was recommended and we kept an expectating attitude so ceasing the process after 4 weeks.
CONCLUSIONS:

Nonveneral sclerosing lymphangitis of the penis is a process of unknown etiology, related to an increase of sexual activity, which is during the erection and it has a self-limited character, so the initial treatment is conservative.

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40.) Mondor's disease of the penis associated with primary syphilis.
========================================================
Int J STD AIDS. 2009 Jul;20(7):510-1. doi: 10.1258/ijsa.2008.008398.

Rani R1.
Author information

1Department of Genitourinary Medicine, Tameside and Glossop PCT, Manchester, UK. r.rani@nhs.net

Abstract

A case of penile Mondor's disease associated with syphilitic chancre is reported. The aetiology and management of Mondor's disease is also discussed.

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41.) Mondor's disease of penis: a forgotten disease.
=========================================================
Sex Transm Infect. 2005 Dec;81(6):480-2.

Kumar B1, Narang T, Radotra BD, Gupta S.
Author information

1Department of Dermatology, Venereology and Leprology, PGIMER, Chandigarh-160 012, India. kumarbhushan@hotmail.com

Abstract
BACKGROUND:

Mondor's disease of penis is an uncommon genital condition involving the penile sulcus in a circumferential manner. Although this disorder is almost always self limited, it is associated with considerable psychological stress and sexual disharmony.
METHODS:

All patients attending the sexually transmitted disease clinic during 1991-2003 were examined for evidence of Mondor's disease of penis. Detailed history and clinical findings were recorded in a specially designed proforma. Histopathological examination and staining with CD31 and CD34 monoclonal antibodies was also done in 11 patients.
RESULTS:

18 out of 1296 patients attending the sexually transmitted diseases (STD) clinic during the study period were found to have penile Mondor's disease, giving an incidence of 1.39%. 17 patients had history of one or more episodes of STDs. Histopathological specimens showed prominent vessels with plump endothelial cells and thickened blood vessel walls. The occasional vessel showed complete occlusion of its lumen.
CONCLUSIONS:

In our study we did not find any evidence of lymphatic involvement. Non-lymphatic vessels, mainly veins, were predominantly involved. In our opinion Mondor's phlebitis of penis or Mondor's disease of penis are better terms to describe the condition rather than non-venereal sclerosing lymphangitis.
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  Produced by Dr. Jose Lapenta R. Dermatologist

                 Maracay Estado Aragua Venezuela 2.017  

           Telf: 02432327287-02432328571   

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