Cat's Claws and Shark Cartilage, Anti tumor and anti-inflammatory effects !
Uña de Gato y Cartilago de Tiburon, efectos antitumorales y
antiinflamatorios !
EDITORIAL ENGLISH
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Hello friends of the Net, DERMAGIC again with you. Today a quite
interesting NON DERMATOLOGIC topic. THE CAT'S CLAW AND THE SHARK
CARTILAGE:
THE CAT'S CLAW is not in fact
the "fingernail of a cat", it is a plant from PERU called UNCARIA
TOMENTOSA, to which have been discovered some beneficent actions for
the organism, being able to be used in: arthritis, rheumatism, bursitis,
gout, immunologic deficiencies, intestinal permeability, intoxications, it
inhibits the platelet aggregation and it acts as anti-inflammatory.in:
USES OF CAT'S CLAW (UNCARIA TOMENTOSA):
1.) arthritis, osteoarthritis.
2.) rheumatism.
3.) bursitis.
4.) gout.
5.) immunologic deficiencies.
6.) intestinal permeability.
7.) intoxicationS.
8.) inhibits the platelet aggregation.
9.) anti-inflammatory.
10.) Anti-cancer activity (breas cancer, lung cancer, thyroid
cancer).
11.) aids.
12.) Diabetes and
others.
CAT'S CLAW CONCLUSIONS:
CAT'S CLAW (UNCARIA TOMENTOSA) is used today for various conditions, including:
It is a NATURAL ANTI-INFLAMMATORY, used as a complementary treatment for arthritis and osteoarthritis.
It also MODULATES and STRENGTHHENS THE IMMUNE SYSTEM, stimulating the production of white blood cells and preventing immunosuppressive states.
It has an ANTIOXIDANT effect, due to its alkaloid and proanthocyanidin content, protecting cells from oxidative stress caused by free radicals.
Use in INFECTIONS: It is used to prevent and treat mild bacterial infections and infections of the urinary, digestive, and respiratory tracts, due to its immune-boosting effect.
Other uses: Relief from chronic diseases such as gastritis, rheumatism, fibroids, polycystic ovary syndrome, support in healing and cell regeneration,
CAT'S CLAW (UNCARIA TOMENTOSA) is used today for various conditions, including:
It is a NATURAL ANTI-INFLAMMATORY, used as a complementary treatment for arthritis and osteoarthritis.
It also MODULATES and STRENGTHHENS THE IMMUNE SYSTEM, stimulating the production of white blood cells and preventing immunosuppressive states.
It has an ANTIOXIDANT effect, due to its alkaloid and proanthocyanidin content, protecting cells from oxidative stress caused by free radicals.
Use in INFECTIONS: It is used to prevent and treat mild bacterial infections and infections of the urinary, digestive, and respiratory tracts, due to its immune-boosting effect.
Other uses: Relief from chronic diseases such as gastritis, rheumatism, fibroids, polycystic ovary syndrome, support in healing and cell regeneration,
Which demonstrate from this plant native from the Peruvian Amazon its
usefulness today as
anti-inflammatory and anti-tumor
effects.
THE SHARK CARTILAGE is not
left behind, as many studies have shown that its components have been used
in conditions such: he has effects scientifically proven ANTI-TUMOR and
ANTI-ANGIOGENESIS activities, its use has even been suggested in PSORIASIS
(reference D). Other effects include: anti-inflammatory, analgesic, and
suppression of atherogenesis.:
USES OF SHARK CARTILAGE:
1,) ANTI-TUMOR-CANCER (tumor growth).
2.) ANTI ANGIOGENESIS (atherosclerosis, suppression of
atherogenesis, TROMBOSIS).
3.) PSORIASIS.
4.) anti-inflammatory.
5.) analgesic.
6.) hemodialysis.
7.) fibrosis.
8.) viral and protozoan infections.
9.) hyperglycemia and others.
CONCLUSIONS OF SHARK CARTILAGE:
Currently, SHARK CARTILAGE has its best effects on joints and OSTEOARTHRITIS. Supplements containing shark cartilage (due to its chondroitin and collagen content) have been shown to be effective in reducing joint pain, and also have analgesic and anti-inflammatory effects.
It has also been tested in PSORIASIS to reduce scaling and itching, but the results are controversial.
Regarding its anti-angiogenesis effects, there is a product called NEOVESTAT or AE-941, a shark cartilage extract that has been studied in CANCER, for its effect on reducing blood vessel formation in tumor lesions. However, it is not approved as a therapy for this condition, and the results of the studies are controversial.
Thus, the greatest benefit of this natural medicine is in JOINT HEALTH, and it is used today by many athletes as a supplement to maintain and improve joint health.
Currently, SHARK CARTILAGE has its best effects on joints and OSTEOARTHRITIS. Supplements containing shark cartilage (due to its chondroitin and collagen content) have been shown to be effective in reducing joint pain, and also have analgesic and anti-inflammatory effects.
It has also been tested in PSORIASIS to reduce scaling and itching, but the results are controversial.
Regarding its anti-angiogenesis effects, there is a product called NEOVESTAT or AE-941, a shark cartilage extract that has been studied in CANCER, for its effect on reducing blood vessel formation in tumor lesions. However, it is not approved as a therapy for this condition, and the results of the studies are controversial.
Thus, the greatest benefit of this natural medicine is in JOINT HEALTH, and it is used today by many athletes as a supplement to maintain and improve joint health.
SUMMARY:
In these references you will know the chemical components of UNCARIA
TOMENTOSA (CAT'S CLAW) and SHARK CARTILAGE and their beneficial effects on
different diseases...So
The really TRUTH is that these products today in day they are a truthful sample that that these ALTERNATIVE medicines are occupying an important place in our SCIENTIFIC WORLD.
Greetings to all !
Dr. Jose Lapenta
EDITORIAL ESPAÑOL
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Hola amigos de la Red, DERMAGIC nuevamente con ustedes. Hoy en día un tema NO DERMATOLÓGICO muy interesante: LA UÑA GATO Y EL CARTÍLAGO DEL TIBURÓN.
Hola amigos de la Red, DERMAGIC nuevamente con ustedes. Hoy en día un tema NO DERMATOLÓGICO muy interesante: LA UÑA GATO Y EL CARTÍLAGO DEL TIBURÓN.
LA UÑA DE GATO no es de
hecho la "uña de un gato", es una planta del PERÚ llamada UNCARIA
TOMENTOSA, a la que se han descubierto algunas acciones benéficas para
el organismo, pudiendo ser utilizada en: artritis, reumatismo, bursitis,
gota, deficiencias inmunológicas, permeabilidad intestinal,
intoxicaciones, inhibe la agregación plaquetaria y
actúa como anti-inflamatorio.
USOS DE LA UÑA DE GATO (UNCARIA TOMENTOSA):
1.) artritis, osteoartritis.
2.) reumatismo.
3.) bursitis.
4.) gota.
5.) deficiencias inmunológicas.
6.) permeabilidad intestinal.
7.) intoxicaciones.
8.) inhibe la agregación plaquetaria.
9.) Antiinflamatorio.
10. Actividad anti cancerígena (cáncer de senos, cáncer de pulmón, cáncer de tiroides).
11.) SIDA.
12.) Diabetes y otros.
CONCLUSIONES UÑA DE GATO:
La UÑA DE GATO (UNCARIA TOMENTOSA) hoy dia se utiliza en diversas
condiciones, a saber:
Es un ANTIINFLAMATORIO NATURAL,
utilizado como tratamiento complementario en artritis y
osteoartritis.
También tiene efectos de MODULACIÓN Y FORTALECIMIENTO DEL SISTEMA INMUNOLÓGICO, estimulado la producción de glóbulos blancos, evitando los estados
inmunosupresivos.
Efecto ANTIOXIDANTE, debido a su contenido de alcaloides y proantocianidinas, protege las células contra el estres oxidativo provocado por los radicales libres.
Uso en INFECCIONES: se utiliza para prevenir y tratar infecciones bacterianas leves e infecciones de las vias urinarias, digestivas y respiratorias, por su efecto de aumentar el estado inmune.
Otros usos: Alivio de enfermedades crónicas, como la gastritis, reumatismo, fibromas, ovario poliquistico, soporte en la cicatrización y regeneración de las células,
Que demuestran que esta planta proveniente de la Amazonía peruana es de
gran utilidad hoy en día debido a sus demostrados efectos
antiinflamatorios y antitumorales.
EL CARTÍLAGO DEL TIBURÓN no se queda atrás, tiene efectos ANTI-TUMORALES y ANTI-ANGIOGÉNESIS comprobados científicamente, incluso se ha sugerido su utilización en la PSORIASIS (referencia D). Otros efectos incluyen: anti-inflamatorio, analgésico, y supresor de la aterogénesis.
EL CARTÍLAGO DEL TIBURÓN no se queda atrás, tiene efectos ANTI-TUMORALES y ANTI-ANGIOGÉNESIS comprobados científicamente, incluso se ha sugerido su utilización en la PSORIASIS (referencia D). Otros efectos incluyen: anti-inflamatorio, analgésico, y supresor de la aterogénesis.
USOS DEL CARTÍLAGO DE TIBURÓN (SHARK CARTILAGE):
1,) ANTI-TUMOR-CANCER (crecimiento tumoral).
2.) ANTI-ANGIOGENESIS (aterosclerosis, supresión de la aterogénesis, TROMBOSIS).
3.) PSORIASIS.
4) antiinflamatorio.
5. analgésico.
6.) hemodiálisis.
7.) fibrosis.
8.) infecciones virales y protozoarias.
9.) hiperglucemia y otros.
2.) ANTI-ANGIOGENESIS (aterosclerosis, supresión de la aterogénesis, TROMBOSIS).
3.) PSORIASIS.
4) antiinflamatorio.
5. analgésico.
6.) hemodiálisis.
7.) fibrosis.
8.) infecciones virales y protozoarias.
9.) hiperglucemia y otros.
CONCLUSIONES CARTÍLAGO DE TIBURÓN:
Actualmente el CARTÍLAGO DE TIBURÓN, presenta sus mejores efectos en
las articulaciones y
OSTEOARTRITIS. los suplementos que contienen cartílago de tiburón (por su contenido de
condroitin y colágeno) han demostrado ser efectivos para reducir el
dolor articular, ademas tiene efectos analgésicos y
antiinflamatorios.
También ha sido probado en la PSORIASIS, para reducir la descamacion y prurito, pero los resultados son
controversiales.
Con respecto a los efectos
ANTI-ANGIOGENESIS,
existe un producto denominado
NEOVESTAT o AE-941 que es
extracto de CARTÍLAGO DE TIBURÓN al cual se ha estudiado en el
CANCER, por su efecto en disminuir la formación de vasos sanguíneos en
las lesiones tumorales (cancer), mas no esta aprobado como terapia para
el mismo, siendo los resultados de los estudios controversiales.
De modo que su mayor utilidad de esta medicina naturista, es en la
SALUD de las ARTICULACIONES,
siendo utilizado hoy dia por muchos deportistas como suplemento para
conservar y mejorar la salud de las articulaciones.
RESUMEN:
En estas referencias conocerás los componentes químicos de
la UNCARIA TOMENTOSA (UÑA DE GATO) y
CARTÍLAGO DE TIBURÓN y sus efectos beneficiosos sobre diferentes
enfermedades ...De modo que:
La VERDAD realmente es que estos productos hoy en día son una muestra verídica que estos medicamentos ALTERNATIVOS están ocupando un lugar importante en nuestro MUNDO CIENTÍFICO.
Saludos a todos. !
Dr. Jose Lapenta.
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BIBLIOGRAPHICAL REFERENCES / REFERENCIAS BIBLIOGRAFICAS
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La VERDAD realmente es que estos productos hoy en día son una muestra verídica que estos medicamentos ALTERNATIVOS están ocupando un lugar importante en nuestro MUNDO CIENTÍFICO.
Saludos a todos. !
Dr. Jose Lapenta.
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BIBLIOGRAPHICAL REFERENCES / REFERENCIAS BIBLIOGRAFICAS
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UNCARIA TOMENTOSA- CAT'S CLAW- UÑA DE GATO
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A. - Cytotoxic effect of different Uncaria tomentosa (cat's claw) extracts, fractions on normal and cancer cells: a systematic review (2025).
B.- Uncaria tomentosa-Adjuvant Treatment for Breast Cancer: Clinical Trial (2012).
C.- Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis (2002).
D. - Development, optimization, and invitro evaluation of novel fast dissolving oral films (FDOF's) of Uncaria tomentosa extract to treat osteoarthritis (2023).
E. - Immunostimulating activity of Uncaria tomentosa in RAW 264.7 macrophages (2023).
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A. - Cytotoxic effect of different Uncaria tomentosa (cat's claw) extracts, fractions on normal and cancer cells: a systematic review (2025).
B.- Uncaria tomentosa-Adjuvant Treatment for Breast Cancer: Clinical Trial (2012).
C.- Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis (2002).
D. - Development, optimization, and invitro evaluation of novel fast dissolving oral films (FDOF's) of Uncaria tomentosa extract to treat osteoarthritis (2023).
E. - Immunostimulating activity of Uncaria tomentosa in RAW 264.7 macrophages (2023).
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1.) Enhanced DNA repair, immune function and reduced toxicity of
C-MED-100, a novel aqueous extract from Uncaria tomentosa.
2.) Uncaria tomentosa (Willd.) D.C.: cat's claw, una de gato, or saventaro.
3.) Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana, Uncaria tomentosa (una de gato).
4.) Uncaria tomentosa (Willd.) DC.--ethnomedicinal use and new pharmacological, toxicological and botanical results.
5.) Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa.
6.) Evaluation of the toxicity of Uncaria tomentosa by bioassays in vitro.
7.) Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a lymphocyte-proliferation-regulating factor.
8.) Depletion of specific binding sites for estrogen receptor by Uncaria tomentosa.
9.) Antiinflammatory actions of cat's claw: the role of NF-kappaB.
10.) Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts.
11.) Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa.
12.) New polyhydroxylated triterpenes from Uncaria tomentosa.
13.) Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda.
14.) [Phytochemical and biological study of Uncaria tomentosa].
15.) The alkaloids of Uncaria tomentosa and their phagocytosis-stimulating action].
16.) CAT'S CLAW (Una de Gato) #K725 INGREDIENTS:
17.) The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line.
18.) Uncaria tomentosa-Adjuvant Treatment for Breast Cancer: Clinical Trial.
19.) Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition.
20.) Cat's claw: an Amazonian vine decreases inflammation in osteoarthritis.
21.) Uncaria tomentosa acts as a potent TNF-alpha inhibitor through NF-kappaB.
22.) The Immunomodulatory Potential of Selected Bioactive Plant-Based Compounds in Breast Cancer: A Review.
23.) Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors.
24.) Quinovic acid glycosides purified fraction from Uncaria tomentosa induces cell death by apoptosis in the T24 human bladder cancer cell line.
25.) Antiproliferative and pro-apoptotic effects of Uncaria tomentosa in human medullary thyroid carcinoma cells.
26.) An active ingredient of Cat's Claw water extracts identification and efficacy of quinic acid.
27.) [Cat's Claw: an herb from the Peruvian Amazon].
28.) Prevention of experimental diabetes by Uncaria tomentosa extract: Th2 polarization, regulatory
T cell preservation or both?
29.) Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects.
30.) Mitraphylline inhibits lipopolysaccharide-mediated activation of primary 31.) Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark.
32.) Synthesis and biological evaluation of quinic acid derivatives as anti-inflammatory agents.
A.- The essential anti-angiogenic strategies in cartilage engineering and osteoarthritic cartilage repair (2022).
2.) Uncaria tomentosa (Willd.) D.C.: cat's claw, una de gato, or saventaro.
3.) Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana, Uncaria tomentosa (una de gato).
4.) Uncaria tomentosa (Willd.) DC.--ethnomedicinal use and new pharmacological, toxicological and botanical results.
5.) Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa.
6.) Evaluation of the toxicity of Uncaria tomentosa by bioassays in vitro.
7.) Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a lymphocyte-proliferation-regulating factor.
8.) Depletion of specific binding sites for estrogen receptor by Uncaria tomentosa.
9.) Antiinflammatory actions of cat's claw: the role of NF-kappaB.
10.) Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts.
11.) Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa.
12.) New polyhydroxylated triterpenes from Uncaria tomentosa.
13.) Plant metabolites. Structure and in vitro antiviral activity of quinovic acid glycosides from Uncaria tomentosa and Guettarda platypoda.
14.) [Phytochemical and biological study of Uncaria tomentosa].
15.) The alkaloids of Uncaria tomentosa and their phagocytosis-stimulating action].
16.) CAT'S CLAW (Una de Gato) #K725 INGREDIENTS:
17.) The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line.
18.) Uncaria tomentosa-Adjuvant Treatment for Breast Cancer: Clinical Trial.
19.) Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition.
20.) Cat's claw: an Amazonian vine decreases inflammation in osteoarthritis.
21.) Uncaria tomentosa acts as a potent TNF-alpha inhibitor through NF-kappaB.
22.) The Immunomodulatory Potential of Selected Bioactive Plant-Based Compounds in Breast Cancer: A Review.
23.) Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors.
24.) Quinovic acid glycosides purified fraction from Uncaria tomentosa induces cell death by apoptosis in the T24 human bladder cancer cell line.
25.) Antiproliferative and pro-apoptotic effects of Uncaria tomentosa in human medullary thyroid carcinoma cells.
26.) An active ingredient of Cat's Claw water extracts identification and efficacy of quinic acid.
27.) [Cat's Claw: an herb from the Peruvian Amazon].
28.) Prevention of experimental diabetes by Uncaria tomentosa extract: Th2 polarization, regulatory
T cell preservation or both?
29.) Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects.
30.) Mitraphylline inhibits lipopolysaccharide-mediated activation of primary 31.) Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark.
32.) Synthesis and biological evaluation of quinic acid derivatives as anti-inflammatory agents.
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CARTÍLAGO DE TIBURÓN / SHARK CARTILAGE
============================================================= A.- The essential anti-angiogenic strategies in cartilage engineering and osteoarthritic cartilage repair (2022).
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